We first broke news to you of XAF5 back in December of last year, unveiling some pretty hefty information about the cream, which may, one day, make blepharoplasty a thing of the past. XAF5 Ointment is a topical cream that’s used under the eyes. Expected to become available some time in 2018, the cream works to fight fat pockets under the eyes, which leads to bags and bulging.
You May Also Like: Bags Vs. Hollows: What's the Difference? The cream was developed by Topokine Therapeutics but was recently acquired by Allergan (the same beauty giant that owns Botox, Latisse and Juvederm) for a reported $85 million. While we hear that the formulation isn’t changing due to the sale of Topokine Therapeutics, the brand further adds to Allergan’s prestigious roster of aesthetic products. “The acquisition of Topokine and its XAF5 technology adds an innovative technology to Allergan’s industry leading mid-to-late stage pipeline of more than 70 programs and bolsters our leadership in medical aesthetics,” says David Nicholson, executive vice president and president, global brands research and development at Allergan. “XAF5 has the potential to be the first topical fat reduction product for the treatment of steatoblepharon, a condition with no current therapeutic options available to patients. We look forward to continuing the outstanding development work conducted by the Topokine team to bring this innovative medical aesthetic treatment to market,” he says.
The proprietary active ingredient penetrates into the fat to shrink the size of the fat cells in under-eye bags. The smaller the fat cells, the less bagging there is. Results can be seen in about five weeks.
If XAF5 Ointment eventually makes it way to market, it would be the first prescription-strength topical medication of its kind, and, perhaps, one day may be able to replace the need for more invasive procedures and surgery.
Thinking About Botox? Juvederm? How to Pick Your Injector
If you’re considering Juvederm, Botox, or any other injection, the person you see for the injection might not seem to matter. After all, you can visit a pharmacist for a flu shot or other vaccination, which is another type of injection, and for the most part, things turn out fine. But, injectables such as Botox or fillers are a completely different story from vaccine injections. You want to use the same level of care and consideration when picking your injector as you would when choosing a surgeon to perform any type of plastic surgery.
Potential Risks You might be wondering, what could possibly go wrong when it comes to choosing an untrained or unqualified injector? The answer is a lot. The face contains many muscles, and if you see a doctor or other injector who isn’t very familiar with the anatomy of the face for a Botox or similar injection, there’s the risk that the injector won’t know which muscles to inject into or even the appropriate amount of the substance to use for the injection, leading to overdone or underdone results, or increasing your risk for side effects.
Another risk of seeing an unlicensed or untrained injector is that he or she may try to use silicone as a filler. While silicone is used as a material in certain implants, it’s not FDA approved for use as an injectable. There are a number of considerable risks or side effects when silicone is injected into the body, such as the development of bumps and scar tissue and the potential for disfigurement.
Warning Signs There are plenty of warning signs or red flags to look out for when choosing an injector for a filler or for a product such as Botox. One of the biggest red flags is that the person offering the injection isn’t any type of medical professional, whether a plastic surgeon or a nurse working under the supervision of a surgeon.
Even if the person is a medical professional, there are a few signs to look out for. The injector should have a considerable amount of proof of experience, such as before and after photos of patients, and references or reviews from patients.
Where the injection is performed is also important. A red flag is if the injector wants to administer the injectable in a non-medical setting, such as at your house or in a hotel room. You always want to work with someone who is working out of a professional office.
A bargain basement price is another thing to be on the lookout for. While an experienced, trained, and licensed medical professional might offer a small discount on injections, he or she won’t offer a price that is too good to be true. The price of injectables are set by the manufacturer. If the price seems way too low or considerably lower than what any other injector is offering, there’s a good chance the product isn’t the real deal.
Questions to Ask There are a number of questions worth asking before you agree to work with an injector. Inquire about the person’s experience and training from the start. Once you’ve been assured that the injector has the background you want, ask about what you need to do after the injection to minimize side effects and whether the injector will see you again if you have any problems. If the injector doesn’t give any post-injection advice or refuses to follow-up with patients, that’s a sure sign that you should look elsewhere.
You can also ask about how to best choose the injectable that’s right for you. While not all qualified injectors offer every product out there today, most offer a variety of options, so that patients can pick the injectable that will provide the results they are after.